So far, the course has been a lot of fun. I like the small group as we can easily have discussions with everyone participating. Our general plan for the course is to learn some biophysics while also learning about open science and modern tools that researchers can use in their research. A mindmap of our initial thoughts is here: http://www.mindmeister.com/106137967/2011-phyc-500
We want to carry out the course as openly as possible, but we don't have a great way of doing that. Especially since our meetings are face to face and we are not setup for video recording or anything like that. But when we do have a chance to contribute openly, we are going to. For example, when we read PLoS papers, we intend to rate them and leave comments, either as a group or individually.
For this week, we read two classic papers by Gilbert Lewis about the effects of heavy water (D2O) on living organisms. These papers are:
- 1. Lewis, G. N. (1933). The biochemistry of water containing hydrogen isotope. Journal of the American Chemical Society, 55(8), 3503–3504. American Chemical Society. doi:10.1021/ja01335a509
- 2. Lewis, G. N. (1934). THE BIOLOGY OF HEAVY WATER. Science (New York, N.Y.), 79(2042), 151-153. doi:10.1126/science.79.2042.151
- Lewis 1934 Science paper: http://www.papercritic.com/mendeley-pub/0a6493d0-6d02-11df-afb8-0026b95d30b2
- Lewis 1933 JACS paper: http://www.papercritic.com/mendeley-pub/241ddab0-6d03-11df-936c-0026b95e484c
- Wikipedia article on Archaea. I am encouraging me and the two students to improve the article if we see opportunities.
- Iddo Friedberg's recent fascinating blog entry, "Why are there no (or almost no) disease-causing Archaea?" We plan to leave a comment on his blog after our discussion.